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Table 2 Comparison between the two studied groups regarding MTX prescription data

From: Does caffeine reduce methotrexate intolerance in patients with rheumatoid arthritis: a randomized controlled study

Demographic variable

Group A (n = 60)

Group B (n = 30)

P value

MTX duration (month)

Mean ± SD

38.3 ± 48.5

30.5 ± 32.0

0.467

Range

4–168

1–120

MTX intolerance duration (month)

Mean ± SD

19.5 ± 18.5

18.3 ± 17.7

0.798

Range

3–60

1–60

Dose of MTX(mg)

Mean ± SD

15.4 ± 4.3

14.7 ± 3.9

0.345

Range

12.5–17.5

12.5–17.5

Route of administration n (%)

IM

4 (6.7%)

4 (13.3%)

0.671

SC

56 (93.3%)

26 (86.7%)

Medications to control intolerance n (%)

None

12 (20%)

6 (20%)

0.532

Pantoprazole

48 (80%)

21 (70%)

Antiemetics

0 (0%)

1 (3.3%)

Pantoprazole + antiemetics

0 (0%)

2 (6.7%)