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Table 1 Investigations

From: A case of completed course multifocal osteonecrosis (MFON) during pregnancy due to primary antiphospholipid syndrome

Investigation

Hematology

CBC shows Hb: 11.9 gm/dl. PLTs: 260 000 /cmm. TLC: 6400/cmm (mild microcytic hypochromic anemia).

TSH: 1.13 iu/ml Free t3 3.18 pg/ml. Free t4: 1.23 ng/dl.

Inflammatory markers:

ESR 1st hour: 24 mm/h. ESR 2nd hour: 48 mm/h. CRP: 6.5 mg/l.

Total lipid profile

Cholesterol: 151 mg/dl. TG: 44 mg/dl. HDL-C: 65 mg/dl. LDL-C: 77 mg/dl.

Renal function

Serum urea: 30 mg/dl. Serum creatinine: 0.8 mg/dl.

Liver function tests

SGOT: 23 U/L. SGPT: U/L.

Viral markers: negative.

ANA: negative

Anti-DsDNA: negative

Anti-sm: negative

C3&4: Normal not consumed

Anti Ro/La : negative

-Anticentromere, anti-scleroderma 70: negative.

Antiphospholipid antibodies:

LA: Positive 55 s (moderate elevated)

-B2 Glycoprotein IgG, IgM : 5.5,5.8 u/ml. –

aCL: negative.

Test was reevaluated after 12 weeks and revealed positive LA and B2 glycoprotein IgG, IgM.

- Protein C& S: normal

- Parathormone: normal (40 pg/ml)

- Serum cortisol level: normal (20mcg/dl)

- Antithrombin: normal.