Neuropathic pain in primary knee osteoarthritis patients: correlation with physical function, quality of life, disease severity, and serum beta nerve growth factor levels

Egyptian Rheumatology and Rehabilitation

Table 6 Correlations of total DN4 score and LANSS score with the studied parameters

	DN4 score		LANSS score
	r_s	P	r_s	P
Symptom duration	0.056	0.647	0.260	0.020*
Educational level	0.061	0.616	0.065	0.590
VAS	0.213	0.077	0.170	0.160
WOMAC pain	0.459	<0.001*	−0.015	0.902
WOMAC stiffness	0.258	0.031*	0.343	0.004*
WOMAC physical function	0.307	0.010*	0.145	0.231
Total WOMAC	0.233	0.052	0.217	0.072
Lequesne pain	0.128	0.291	0.344	0.004*
Lequesne maximum distance walked	0.017	0.891	0.213	0.076
Lequesne daily activity	0.062	0.608	0.143	0.239
Total Lequesne	0.060	0.619	0.322	0.007*
OAKHQOL physical	0.017	0.891	−0.258	0.031*
OAKHQOL mental health	0.029	0.81	0.254-	0.034*
OAKHQOL pain	−0.337	0.004*	−0.074	0.541
OAKHQOL social support	−0.107	0.376	0.283-	0.018*
OAKHQOL social function	−0.12	0.323	0.145-	0.232
Total OAKHQOL	−0.073	0.551	0.261-	0.029*
KL scale	0.107	0.379	0.0 99	0.414
βNGF	0.341	0.004*	0.313	0.008*

Spearman’s correlation test; *significant P value ≤ 0.05, VAS visual analogue scale, WOMAC Western Ontario and McMaster Universities Osteoarthritis Index, OAKHQOL osteoarthritis knee hip quality of life, DN4 Douleur Neuropathique 4, LANSS Leeds assessment neuropathic pain symptoms and signs, KL= Kellgren–Lawrence, βNGF= beta nerve growth factor