Egyptian consensus on treat-to-target approach for osteoporosis: a clinical practice guideline from the Egyptian Academy of bone health and metabolic bone diseases

Egyptian Rheumatology and Rehabilitation

Table 4 Approved interventions for glucocorticoid-induced osteoporosis and its effect on BMD and fracture risk

Intervention	Spine BMD	Hip BMD	Vertebral fracture	Non-vertebral fracture
Alendronate	A	A	B^b	NAE
Risedronate	A	A	A^b	NAE
Teriparatide	A^a	A^a	A^{a, b}	NAE
Zoledronic acid	A^a	A^a	NAE	NAE
Denosumab	A^a	A^a	NAE	NAE

A grade A recommendation, B grade B recommendation, NAE not adequately evaluated
^aComparator study
^bNot a primary endpoint