Egyptian consensus on treat-to-target approach for osteoporosis: a clinical practice guideline from the Egyptian Academy of bone health and metabolic bone diseases

Egyptian Rheumatology and Rehabilitation

Table 3 The anti-fracture efficacy of the approved therapies for postmenopausal women with osteoporosis when given with calcium and vitamin D

Intervention	Vertebral fracture	Non-vertebral fracture	Hip fracture
Alendronate	A	A	A
Ibandronate	A	A*	NAE*
Risedronate	A	A	A
Zoledronic acid	A	A	A
Denosumab	A	A	A
HRT	A	A	A
Raloxifene	A	NAE	NAE
Teriparatide	A	A	NAE
Romosozumab	A	A	A

A grade A recommendation, NAE not adequately evaluated, HRT hormone replacement therapy
^*In subsets of patients only (post hoc analysis)