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Egyptian Rheumatology and Rehabilitation

Table 2 Agreement (sensitivity, specificity) for different parameters to predict cases (vs control)

From: Evaluation of serum14-3-3η protein and Sema3A levels in rheumatoid arthritis: diagnostic and prognostic value

 

AUC

p

95% C.I

Cut off

Sensitivity

Specificity

PPV

NPV

RF

0.870

< 0.001*

0.778–0.961

> 7

80.0

85.71

87.8

76.9

ACCP

0.855

< 0.001*

0.764–0.946

> 22

84.44

88.57

90.5

81.6

14-3-3 η

0.957

< 0.001*

0.916–0.997

> 0.24

88.89

91.43

93.0

86.5

Sema3A

0.854

< 0.001*

0.755–0.953

≤ 5.8

82.82

80.0

84.1

77.8

  1. AUC Area under a curve, p value probability value, CI Confidence intervals, NPV Negative predictive value, PPV Positive predictive value
  2. *Statistically significant at p ≤ 0.05
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